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Abstract

Evaluation of Erythrocyte and Thrombocyte Parameters in Pediatric Patients with Diabetes Mellitus


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Authors
Seher Erdogan, Fatma Dursun, Heves Kırmızıpekmez, Sirin Guven, Ulku Miray Yıldırım

J Clin Anal Med 2017;8(2):98-101
doi:10.4328/JCAM.4753

Abstract
Aim: To analyze erythrocyte and thrombocyte parameters in patients with diabetes, diabetic ketoacidosis, and controls. Material and Method: Patients who were diagnosed as having diabetic ketoacidosis (DKA) in the pediatric emergency clinic between January 2015 and January 2016 were included in group 1; patients with type 1 diabetes mellitus (DM) who consulted the pediatric endocrinology outpatient clinic for routine controls were included in group 2, and control patients were in group 3. Results: A total of 108 patients comprising 36 patients with DKA, 37 patients with DM, and 35 controls were involved in the study. The mean platelet volume (MPV) of the control group was significantly lower than the DKA (p= 0.001) and DM (p= 0.001) groups (p<0.01). The mean corpuscular hemoglobin concentration (MCHC) was significantly higher in the DKA group than in the DM group (p= 0.017), and the mean value of platelet distribution width (PDW) in the DKA group was found higher than that in the DM and control groups (p<0.01). There was no statistically significant difference between the groups in terms of red cell distribution width (RDW), mean corpuscular volume (MCV), and red blood cell distribution width/mean corpuscular volume (RDW/MCV) levels (p>0.05). Discussion: An inflammatory marker, MPV, was found higher in the DKA and diabetic groups than in the normal population. High levels of MPV, RDW, PDW, and MCHC increased the risk of DKA incidence.

Keywords : Diabetes Mellitus, Mean Platelet Volume, Platelet Distribution Width, Red Cell Distribution Width,

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How to Cite :
Seher Erdogan, Fatma Dursun, Heves Kırmızıpekmez, Sirin Guven, Ulku Miray Yıldırım, Evaluation of Erythrocyte and Thrombocyte Parameters in Pediatric Patients with Diabetes Mellitus, J Clin Anal Med 2017;8.(2):98-101