Aim: To determine the antenatal depressive mood frequency and associated risk factors in a semi-urban region in the capital of our country.Material and Method: Six hundred pregnant women within their third trimester were included. Depression levels were evaluated according to the "Edinburgh Postnatal Depression Scale". Those scoring 13 and over were considered as depressed. Depressed and non-depressed pregnant women were compared according to socio-demographic characteristics, family, and medical features.Results: One hundred and fifty-three patients out of 600 were found to be depressive (25.5%). Low/advanced maternal age, low education level and unemployment of the women/husband, involuntary marriage, living with spouse's relatives, unplanned pregnancy, and existence of a diagnosed chronic disease were found to increase the frequency of depression (p<0.001). Discussion: Because of its high frequency among women in the third trimester, depression screening should be included in prenatal care routine programs and accessible diagnosis and treatment services should be provided for pregnant women diagnosed with depressive mood.