Objective: Admission hyperglycemia is a common clinical condition after acute myocardial infarction (MI). The aim of this study was to study the relationship between admission glucose level and ST-segment resolution in ST-segment elevation MI (STEMI) patients treated with thrombolytics within 12 hours of the onset of chest pain.
Patients and Methods: Data from 232 patients with a diagnosis of first STEMI were analyzed in this prospective study. All of the patients received thrombolytic therapy within 12 hours of the onset of chest pain. The patients were divided into two groups based on the presence of ≥50% ST-segment resolution.
Results: Patients with <50% ST-segment resolution had higher admission glucose levels than patients with ≥50% ST-segment resolution (182.57±76.33 mg/dl vs. 150.44±53.95 mg/dl, respectively; p<0.001).
Discussion: In the present study, we found that higher admission glucose levels were associated with impaired ST-segment resolution in STEMI patients treated with thrombolytics.
Conclusion: Our findings suggest that higher glucose values may be related to thrombolytic failure; further studies are needed.