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Abstract

Effects Of A Novel Seven-Species Probiotic Against Oropharyngeal Bacterial Infestation


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Authors
Mansoor Masjedi, Shahin Raoufi, Gholamreza Dabiri, Majid Yazdani, Pooya Vatankhah

J Clin Anal Med 2017;8(Suppl 4):-
doi:10.4328/JCAM.5472

Abstract

Effects of a Novel Seven-Species Probiotic Against Oropharyngeal Bacterial Infestation in Adult Trauma Intensive Care Unit Patients; A Randomized Double Blind Clinical Trial

 

Abstract

Aim: Ventilator-associated pneumonia results from invasion of the lower respiratory tract and lung parenchyma by microorganisms. The aim of our study was to investigate the efficacy of a new probiotic combination containing 7 bacterial species against oropharyngeal bacterial infestation in adult trauma intensive care unit patients.

Material and Methods: One hundred and fifty patients were placed in the two treatment groups by computerized random allocation in a 1:1 ratio and received either probiotics or placebo. Oropharyngeal cultures were taken on the 1st (before the intervention), 4th, and 6th days of admission.

Results: The culture results of the 1st, 4th, and 6th days were comparable and no statistically significant difference was noticed in the two arms of the study.

Conclusion: Based on the results of our study, Administration of probiotics to alter early oropharyngeal cavity infestation with PPM in adult trauma patients admitted in Intensive Care Unit appears to be non-efficacious, even when a 7- species combination is used.



Keywords : probiotics, bacteria, culture, trauma, Intensive Care Unit,

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How to Cite :
Mansoor Masjedi, Shahin Raoufi, Gholamreza Dabiri, Majid Yazdani, Pooya Vatankhah, Effects Of A Novel Seven-Species Probiotic Against Oropharyngeal Bacterial Infestation, J Clin Anal Med 2017;8.(Suppl 4):-