Aim: Sella turcica is a saddle-like depression on the middle cranial fossa and on the upper surface of the sphenoid bone. It is a bone structure closely related to the pituitary gland and have anatomical and clinical importance. Empty sella syndrome is large or deformed radiologic image of sella turcica which has been partially or completely filled with cerebrospinal fluid. The purpose of our research is to investigate sella turcica morphometry in empty sella syndrome and to obtain a conclusion according to the literature on reasons and consequences of changing in sella turcica. Material and Method: In our study, computed tomography images of 33 adult participants with empty sella syndrome and 30 adult participants with normal findings as control group were used. Sella length, height, anterior-median-posterior heights, area, depth and anteroposterior diameter were measured in both groups.Results: In all variables, the values determined in the empty sella syndrome group were higher than the control group, but we found that sella depth and anterior-median-posterior heights were statistically significant. Discussion: It is known that sella turcica in empty sella syndrome expands. But we could not reach a morphometric study that shows this. We believe that the values detected in this study will be referred to physicians working on pituitary and sella surgeries.