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Abstract

Prognostic value of mean platelet volume, neutrophil to lymphocyte ratio and platelet to-lymphocyte

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Authors
Songul Ozyurt, Yasin Yildiz, Ugur Kostakoglu, Ayse Erturk, Aysegul Cicek Copur , Ilknur Esen Yildiz

J Clin Anal Med 2018;9(5):363-368
doi:10.4328/JCAM.5719

Abstract

ABSTRACT

Objective: Acute bacterial and viral infections have usually been associated with elevations of the mean platelet volume. We correlated infection with influenza changes in mean platelet volume (MPV), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR), and whether these might be predictors for the duration of hospitalization or mortality.

Methods: A total of 122 influenza patients (54 males and 68 females) 87childs and 35 adults  and age-gender-matched healthy subjects 42 healthy individuals (18 males and 24 females) in  25 childs and 17 adults were included in the study. Hematologic tests were conducted on patients and controls. Linear regression analysis was used to determine independent predictors of hospitalization.

Results: The MPV was significantly higher in influenza patients [10.7 (min/max 7.5-15) fL ] as well as healthy control group [7.8(min/max 5.7-10.8)fL, p<0.001]. The NLR and PLR were similar in both groups. There was no correlation between MPV, NLR and PLR and mortality. Predictors of hospitalization were determined as neutrophil level (NL) and NLR and PLR ratios (p = 0.00, p = 0.035 and p = 0.041, respectively).

Conclusions: Neutrophil, MPV, NLR and PLR were significantly higher in influenza group. While the MPV was not determined as the length of stay and mortality in the patient, the height of NLR and PLR and increased neutrophil levels predicted the duration of hospitalization.

 



Keywords : influenza; , mean platelet volume;, neutrophil to lymphocyte ratio;, platelet to-lymphocyte ratio ,

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How to Cite :
Songul Ozyurt, Yasin Yildiz, Ugur Kostakoglu, Ayse Erturk, Aysegul Cicek Copur , Ilknur Esen Yildiz, Prognostic value of mean platelet volume, neutrophil to lymphocyte ratio and platelet to-lymphocyte , J Clin Anal Med 2018;9.(5):363-368