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Abstract

Procalcitonin, c-reactive protein, leukocyte, mean platelet volume levels in bloodstream infections


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Authors
Arzu Ýrvem, Sabahat AKSARAY

J Clin Anal Med 2018;9(5):391-395
doi:10.4328/JCAM.5766

Abstract

Objective: Serum Procalcitonin (PCT), C-Reactive Protein (CRP), Leukocyte (WBC), Mean Platelet Volume (MPV) were evaluated in sepsis patients. Materials and methods: We included 126 episodes of bacteremia from 126 patients with sepsis in this study. Medical records of patients who had bacteremia caused by Gram-negative bacteria (GN), Gram-positive bacteria (GP) or fungi were reviewed, and information about PCT and other inflammatory markers was recorded. Mann-Whitney U test and Spearman's correlation analysis were used for Statistical analysis. Findings: Microorganism; 60.4% of the cases (n=76) were GN, 31.7% (n=40) were GP and 7.9% (n=10) were yeast. There was a statistically significant difference between PCT, CRP, and MPV levels according to the microorganism (p=0,001, p<0,01). Results: According to the microorganism gram positivity cutoff points were determined for PCT as (≤12,17), CRP as (≤9,70) and MPV as (≤9,32). In bilateral comparisons, there was a significant increase in GN and yeast sepsis, while a significant low level was found in GP sepsis. There was no significant difference between GN and yeast. When the measurements of PCT according to bacterial species are examined; The highest measurement was found to be 44.6 ng/ml with Escherichia coli bacteria, and it was followed by Candida bacteria with 12,6 ng/m.



Keywords : Microorganisms, Procalcitonin, C-reactive protein, Leukocyte, Mean platelet volume,

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How to Cite :
Arzu Ýrvem, Sabahat AKSARAY, Procalcitonin, c-reactive protein, leukocyte, mean platelet volume levels in bloodstream infections, J Clin Anal Med 2018;9.(5):391-395