Aim: We aimed to demonstrate the relation between NLR and Pneumonia Severity Index (PSI), Confusion, Blood Urea Nitrogen, Respiratory Rate, Blood Pressure, Age ≥65 (CURB-65), Predisposition, Infection, Response, Organ dysfunction scores (PIRO) in patients with community-acquired pneumonia (CAP).
Material Method: Total 100 CAP patients were included in the study. The patients underwent the physical examinations and the medical histories were taken at the first moment of hospitalization. The biochemistry, hemogram, arterial blood gas examinations were studied. PSI, CURB-65, PIRO scores were calculated.
Result: 67 patients were recruited from patient clinic and 33 from intensive care units
were followed. A positive correlation was found between NLR and CURB-65, PIRO, PSI (r:0.354 p<0.001, r:0.290 p:0.003, r:0.302 p:0.002 respectively). In the ROC curve analysis, for the estimation of CURB-65 > 2 NLR had 6,26 predictive value (AUC:0,762, 95% CI:0,662-0,863, p<0,001), 76% sensitivity, 60% specificity, for the estimation of PIRO >3 NLR had 6,67 predictive value (AUC:0,687, 95% CI:0,569-0,806, p=0,013), 67% sensitivity, 60% specificity, for the estimation of PSI >3 NLR had 5,55 predictive value (AUC:0,637, 95% CI:0,523-0,750, p<0,001), 62% sensitivity, %58 specificity. The patients died had significantly higher NLR level in proportion to the ones survived (p=0.010). However, for the estimation of death NLR was not superior to scores.
Conclusion: NLR, a non-specific inflammatory marker is closely related to the scores regarding the severity of the patients with CAP. Although it is not superior to the score systems in the estimation of death, it can be used with the scores for the same aim.